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OVOIL™

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OVOIL™ 100% paraffin oil of highest quality. Extensively tested. Proven excellent embryo development. The importance of oil for IVF outcome : Most clinics use oil to cover embryo culture dishes in order to maintain stable temperature, osmolality and pH. The quality of such oil is very important for IVF success. The oil types commonly used are mineral oil, paraffin oil or a mixture of both these oil types. Oil is not just oil : Oils from 5 different manufacturers were tested and embryo development and viability was evaluated1, se Fig 1 and 2. OVOIL™ showed significantly better development ( p < 0.01), for all embryo viability parameters studied, number of cells in the trophectoderm and in the inner cell mass, and total number of cells in the blastocysts. Paraffin oil gives better development : Paraffin oil and mineral oil are chemically slightly different. The polycarbon lipid tail of mineral oil contains more unsaturated bonds than the more saturated paraffin oil. This makes mineral oil more unstable and prone to attack by free oxygen radicals and photo-oxidation than stable paraffin oil. In a study by Tae et al. 2 published in 2005, mouse embryo development was studied in cultures overlaid with either washed mineral or sterile paraffin oil. Sterile filtered paraffin oil overlay resulted in significantly higher (p < 0.05) development rate to morula (44.8% versus 30.6%) and blastocyst (32.8% versus 21.7%) than washed mineral oil. Purpose - For covering of medium during in vitro fertilisation and micro-manipulation procedures. Description - Sterile light paraffin oil. Application - Ready-to-use after pre-equilibration at +37°C and 5 % CO2, 6 % CO2 or ambient atmosphere, depending on the intended use. Storage - Store dark at +2 to +8°C.

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G-1™ PLUS

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G-1™ PLUS G-1™ PLUS G-1™ provides the carbohydrates, amino acids and hyaluronan to support the embryo during the first critical stage of development. G-1™ PLUS contains Human Serum Albumin. Purpose - For culture of embryos from the pronucleate stage to day 2 or day 3. Description - Bicarbonate buffered medium containing hyaluronan. Application - For use after pre-equilibration at +37ºC and 6 % CO2. Supplement G-1™ with G-MM™ or HSA-solution™. Storage - Store dark at +2 to +8ºC.

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G-2™ PLUS

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G-2™ PLUS G-2™ PLUS G-2™ provides the embryo with a wide range of amino acids and hyaluronan for blastocyst development. G-2™ PLUS contains Human Serum Albumin. Purpose - For culture of embryos from day 3 to the blastocyst stage. Description - Bicarbonate buffered medium containing hyaluronan. Application - For use after pre-equilibration at +37ºC and 6 % CO2. Storage - Store dark at +2 to +8ºC.

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G-IVF™ PLUS

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G-IVF™ PLUS G-IVF™ PLUS Fertilisation medium containing all components necessary to support oocyte and sperm function during fertilisation. G-IVF™ PLUS contains Human Serum Albumin. Purpose - For preparation and handling of gametes and for in vitro fertilisation. Description - Bicarbonate buffered medium. Application - For use after pre-equilibration at +37ºC and 6 % CO2. Storage - Store dark at +2 to +8ºC.

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G-MOPS™

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G-MOPS™ G-MOPS™ Product Information A pH stable handling medium designed to support the handling and manipulation of oocytes and embryos outside the incubator. Purpose - For handling and manipulating oocytes and embryos in ambient atmosphere. Description - MOPS buffered medium. Application - For oocyte collection after temperature equilibration at +37°C and ambient atmosphere. G-MOPS™ only - For gamete and embryo manipulation after the addition of G-MM™ or HSA-solution™ and temperature equilibration at +37°C and ambient atmosphere. Storage - Store dark at +2 to +8ºC.

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G-GAMETE™

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G-GAMETE™ G-GAMETE™ A pH stable handling media to support oocytes and embryos outside of the incubator. Purpose - For handling and manipulating oocytes and embryos in ambient atmosphere. Description - MOPS buffered medium containing human serum albumin. Application - For use after equilibration at +37ºC and 6% CO2. Storage - Store dark at +2 to +8ºC.

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G-PGD™

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G-PGD™ G-PGD™ G-PGD™ is designed for optimising embryo biopsy and maintains pH during the biopsy procedure. Purpose - For embryo biopsy. Description - Calcium- and Magnesium-free MOPS buffered medium. Application - For use after the addition of G-MM™ or HSA-solution™ and temperature equilibration at +37ºC and ambient atmospere. Storage - Store dark at +2 to +8ºC.

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HSA-solution™

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HSA-solution™ HSA-solution™ EmbryoGlue® - for increased take-home baby rate Purpose - For use in assisted reproductive procedures which include gamete and embryo manipulation. These procedures include the use of HSA-solution™ as a supplement for culture medium. Not for use as an injectable product. Description - Human Serum Albumin solution (100 mg/mL). Application - For supplementation of gamete and embryo media. Storage - Store dark at +2 to +8ºC.

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G-MM™

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G-MM™ G-MM™ G-MM™ is a recombinant supplement for all embryo culture media. Purpose - For use in assisted reproductive procedures which include gamete and embryo manipulation. These procedures include the use of G-MM™ as a supplement for culture medium. Not for use as an injectable product. Description - Recombinant Human Albumin solution (50 mg/mL). Application - For supplementation of gamete and embryo media. Storage - Store dark at +2 to +8ºC.

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G-RINSE™

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G-RINSE™ G-RINSE™ For rinsing of contact materials and washing of the cervix before oocyte aspiration and embryo transfer. Purpose - Solution for rinsing of contact materials and for washing of the cervix. Not for culture. Description - Bicarbonate buffered salt solution Application - For use after pre-equilibration at +37ºC and 6 % CO2. Storage - Store dark at +2 to +8ºC.

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